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Throat Irritation Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. Elderly individuals have more side effects when taking Zanaflex (tizanidine). 6. Dizziness. These medications may interact and cause very harmful effects. Dizzy 3. All drugs may cause side effects. O 0. In such cases, withdrawal symptoms (such as anxiety, tremor, increased blood pressure/heart rate/muscle tenseness) may occur if you suddenly stop using this medication. Consult your doctor or pharmacist for more details, and report any withdra… Do not take tizanidine more than 36 milligrams a day or more than 3 dosages in a 24-hour period. Tizanidine oral tablet may cause drowsiness. Acorda Therapeutics, Hawthorne, NY. Includes Zanaflex side effects, interactions and indications. [Ref], Very common (10% or more): Somnolence (up to 48%), dizziness (up to 16%), Common (1% to 10%): Speech disorder, dyskinesia, Frequency not reported: Headache, ataxia, dysarthria, Postmarketing reports: Convulsion, paresthesia, tremor[Ref], Very common (10% or more): Dry mouth (up to 49%), Common (1% to 10%): Vomiting, constipation, Rare (0.01% to 0.1%): Nausea, gastrointestinal disorder, Frequency not reported: Abdominal pain, loss of appetite[Ref], Common (1% to 10%): Liver test abnormality, Very rare (less than 0.01%): Hepatic failure, Common (1% to 10%): Bradycardia, hypotension, tachycardia, Postmarketing reports: Syncope, ventricular tachycardia, QT prolongation[Ref], Frequency not reported: Accommodation disorder[Ref], Postmarketing reports: Stevens Johnson Syndrome, exfoliative dermatitis, rash[Ref], Frequency not reported: Drug withdrawal reactions including rebound hypertension, tachycardia, and hypertonia[Ref], Common (1% to 10%): Urinary tract infection, urinary frequency[Ref], Common (1% to 10%): Pharyngitis, rhinitis[Ref], Frequency not reported: Anaphylaxis, hypersensitivity reactions, Postmarketing reports: Anaphylactic Reaction[Ref], Common (1% to 10%): Infection, flu syndrome[Ref], Rare (0.01% to 0.1%): Hallucinations, insomnia, sleep disorders, Frequency not reported: Confusional state. Dizziness. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Side Effects What are the side effects of Tizanidine (Zanaflex)?. What are some other side effects of tizanidine? What Are Side Effects of Zanaflex? Taking tizanidine with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Tizanidine may cause dryness of the mouth. Combining such drugs can lead to an intensification of side effects, which, if not quickly addressed, can lead to drowsiness, lethargy, confusion, hypotension, bradycardia, respiratory depression, and coma. cyclobenzaprine, tizanidine, diazepam, Flexeril, methocarbamol, Soma. Tizanidine Side Effects D… For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. 8. Zanaflex (tizanidine) can lower blood pressure, so be careful if you are already on a blood pressure medication. Rash 10. It also possesses a moderate central analgesic effect. 2. Need to be consistent every day in taking this with or without food. As you should expect from most drugs, Tizanidine produces side effects. Description: Tizanidine is an α 2-adrenergic agonist that acts on the spinal and supraspinal levels to block excitatory interneurons.It reduces spasticity by increasing presynaptic inhibition and has great effects in the polysynaptic pathways. Tizanidine has … Do not stop taking this medication without consulting your doctor. Other side effects include: constipation, and increased liver enzymes. "Product Information. Tizanidine is an inexpensive drug used to manage spasticity (unusual tightness, stiffness, or rigidity of muscles).It is more popular than comparable drugs. To reduce your the side effects of this tizanidine, your doctor may prescribe you this medication at a low dose and gradually increase your dose. Tizanidine, also known by its trade name Zanaflex, is a muscle relaxant medication used for treating muscle spasticity.Tizanidine is legally available with a prescription in the United States, but drug dealers sell the drug for illicit use.. Tizanidine is an especially toxic medication with many serious side effects and dangerous interactions with other medications, such as birth control pills. It may also cause other side effects. received an overall rating of 6 out of 10 stars from 138 reviews. Side effects, drug interactions , dosage, storage, and pregnancy safety information should be reviewed prior to taking this medication. All rights reserved. Data sources include IBM Watson Micromedex (updated 2 Feb 2021), Cerner Multum™ (updated 3 Feb 2021), ASHP (updated 29 Jan 2021) and others. Nausea. You may report them to the FDA. TIZANIDINE/ZILEUTON Below is a summary of known side effects for Tizanidine. vitamins, herbal supplements, etc. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur while taking tizanidine: Tizanidine is a skeletal muscle relaxant used in the treatment of spasticity, a condition where the muscles are contracted continuously. Tizanidine side effects. Drowsiness 4. Dizziness. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. MRI scans of the spinal cord in a patient with MS. A suggests that medical marijuana is effective for chronic pain, which persists even after an injury should have healed and for which opioids are already not a great treatment. Take tizanidine exactly as directed. Tizanidine is a dangerous drug with many side effects and toxic interactions with other medications. Disturbances of the gut such as diarrhoea, constipation, nausea, vomiting or abdominal pain. Medically reviewed by Drugs.com. However, if dry mouth continues for more than 2 weeks, check with your medical doctor or dentist. See below for a comprehensive list of adverse effects. uncontrolled muscle movements. Tizanidine (Zanaflex) is a drug used to treat the tendency of muscles to spasm, typically resulting from neurological problems. Applies to tizanidine: oral capsule, oral tablet. Effectiveness appears similar to baclofen or diazepam. It is used to treat the spasticity especially due to neurological disorders, and in painful muscle spasms of spinal origin. Available for Android and iOS devices. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: The most frequently reported adverse reactions include dry mouth, somnolence/sedation, asthenia, and dizziness. Generic tizanidine is covered by most Medicare and insurance plans, … Low blood pressure (hypotension). CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Tizanidine may interact with other drugs that you are currently taking, which can change how your drug works or increase your risk for serious side effects. Check with your doctor immediately if any of the following side effects occur while taking tizanidine: Get emergency help immediately if any of the following symptoms of overdose occur while taking tizanidine: Some side effects of tizanidine may occur that usually do not need medical attention. Some people who have insomnia will abuse Tizanidine. WebMD does not provide medical advice, diagnosis or treatment. How to take tizanidine. Adverse Reactions In multiple dose, placebo-controlled clinical studies, 264 patients were treated with tizanidine and 261 with placebo. Before using Tizanidine, inform your doctor about your current list of medications, over the counter products (e.g. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Along with its needed effects, tizanidine may cause some unwanted effects. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The more common side effects of tizanidine can … Tizanidine reduces nerve activity in the spinal cord, which helps to reduce muscle spasms. Because muscle relaxers like tizanidine work quickly, the effects are likely to wear off within a few hours of taking a capsule or tablet. Feeling tired or weak. Things to remember when you fill your prescription. Tizanidine has a large number of common and prevalent side effects including: Low blood pressure, especially with dose increases Rebound high blood pressure when decreasing the dose pregnancy, upcoming surgery, etc. Drowsiness. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Tizanidine may cause dryness of the mouth. 5. It is a short-acting drug, and its effects are strongest between 1 and 3 hours after it is taken. Feeling sleepy. Switching between taking tizanidine with food and taking it without food can make the medicine less effective or cause increased side effects. Inducing Of A Relaxed Easy State 8. Tizanidine – or Zanaflex, the brand name — does not cure these muscle problems but may allow other treatments, such as physical therapy, to help improve the … This is not a complete list of side effects and others may occur. Find patient medical information for tizanidine oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Common side effects of Zanaflex may include: anxiousness, nervousness, numbness or tingling, stomach pain, diarrhea, constipation, vomiting, See what others have said about , including the effectiveness, ease of use and side effects. © 2005 - 2019 WebMD LLC. Last updated on Sep 25, 2020. Zanaflex (tizanidine) is a short-acting muscle relaxer used to treat spasticity by temporarily relaxing muscle tone. Tizanidine falls under a classification of drugs known as alpha-2-adrenergic agonists. 2. Follow your doctor’s instructions carefully. Feeling tired or weak. Applies to tizanidine: oral capsule, oral tabletAlong with its needed effects, tizanidine may cause some unwanted effects. If experienced, these tend to have a Less Severe expression 1. Common side effects of tizanidine include: low blood pressure, dry mouth, dizziness, sleepiness, weakness, fatigue, blurred vision, and; constipation. More common side effects. Zanaflex (tizanidine)." Feeling Weak 7. Dry mouth. Just because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Tizanidine (Zanaflex) is a drug used to treat the tendency of muscles to spasm, typically resulting from neurological problems. However, many people have no side effects or only have minor side effects. It is taken by mouth. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for TIZANIDINE. Tizanidine side effects are also connected with its effects to the brain. Withdrawal from tizanidine also carries significant potential for harm. Zanaflex (tizanidine hydrochloride) is a muscle relaxant used to treat muscle tightness and cramping (spasm) caused by conditions such as multiple sclerosis or spinal injury. Inflammation Of The Nose 9. This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. If experienced, these tend to have a Severe expression, If experienced, these tend to have a Less Severe expression. 4. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. After it became ineffective singularly, I began using it in combination with Keppra & I'm still realizing positive results using this regimen. The studies have proven that tizanidine is efficient as other anti-spasm medications (such as baclofen and diazepam) but much better tolerated by the patients. Common side effects include dry mouth, sleepiness, weakness, and dizziness. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Dry mouth. Tizanidine(Zanaflex) generic is a centrally acting muscle relaxant. All drugs may cause side effects. Therefore, most people take it right before daily activities only when they need to reduce symptoms such as muscle spasms. This medicine is not recommended for use in children and adolescents. 7. I do experience some minor muscle fatigue & occasional dry mouth while using Zanaflex, however nothing close in terems of negative side effects … Fatigue. Switching between tizanidine tablets and … It is usually taken consistently either always with or always without food two or three times a day. Tizanidine is a short-acting drug for the management of spasticity.Because of the short duration of effect, treatment with tizanidine should be reserved for those daily activities and times when relief of spasticity is most important. Selected from data included with permission and copyrighted by First Databank, Inc. These side effects may go away during treatment as your body adjusts to the medicine. Some side effects may not be reported. 3. Although not all of these side effects may occur, if they do occur they may need medical attention. Ask your doctor before taking a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression , or seizures . Buy Tizanidine Online. Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. Tizanidine, sold under the brand name Zanaflex among others, is a medication that is used to treat muscle spasticity due to spinal cord injury or multiple sclerosis. Tizanidine comes as a tablet and a capsule to take by mouth. Common tizanidine side effects may include: drowsiness, dizziness, weakness; feeling nervous; blurred vision; flu-like symptoms; dry mouth, trouble speaking; abnormal liver function tests; runny nose, sore throat; urination problems; vomiting, constipation; or. What are some other side effects of Tizanidine? To prevent withdrawal reactions, your doctor may reduce your dose gradually. That’s because a common side effect of the drug is sleepiness. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Dry mouth. Below is a summary of known side effects for Tizanidine. Tizanidine is classified as a controlled substance that is only legally available with a prescription. This medication does not cure the illness, but provides the pain relief to the patient. Do not take more or less of it or take it more often than prescribed by your doctor. Some side effects of Zanaflex are common and do not put the patient’s life in any danger, while others may need immediate medical attention. Cerner Multum, Inc. "UK Summary of Product Characteristics." Feeling sleepy. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Know uses, side effects, dosage, contraindications, substitutes, benefit, interactions, purpose, drug interactions, precautions, warnings etc. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. However, if dry mouth continues for more than 2 weeks, check with your medical doctor or dentist. However, many people have no side effects or only have minor side effects. Constipation 2. 1. Dysarthria 6. ).Some health conditions may make you more susceptible to the side-effects of the drug. We comply with the HONcode standard for trustworthy health information -, irregular, fast or slow, or shallow breathing, Dizziness or lightheadedness, especially when getting up from a lying or sitting position. Commonly reported side effects of tizanidine include: bradycardia, dizziness, drowsiness, hypotension, asthenia, fatigue, and xerostomia. Medicines and their possible side effects can affect individual people in different ways. Tizanidine used for its high side effect, when combined with other CNS depressants, can result in fatality. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter, A Type Of Speech Disorder Called Dysarthria, A Type Of Abnormal Movement Disorder Called Dyskinesia, Orthostatic Hypotension, A Form Of Low Blood Pressure, A Significant Type Of Allergic Reaction Called Anaphylaxis, A Skin Disorder With Blistering And Peeling Skin Called Stevens-Johnson Syndrome, A Type Of Allergic Reaction Called Angioedema, Inflammation Of The Liver Called Hepatitis. Side effects, drug interactions , dosage, storage, and pregnancy safety information should be reviewed prior to taking this medication. Some severe side effects of the drug you must watch out for include: Hallucinations (seeing things that aren’t real) Delusions (believing things that are not real) It will give you more information about tizanidine and will provide you with a full list of the side-effects which you may experience from taking it. Although Zanaflex is an efficient drug for treating muscle spasms caused by multiple sclerosis or spinal cord injury, the patient might also experience some tizanidine adverse effects. 1. Adverse Reactions In multiple dose, placebo-controlled clinical studies, 264 patients were treated with tizanidine and 261 with placebo. Dry Mouth 5. While some may be moderate, others may be more severe. The following are some of the side effects that are known to be associated with this medicine. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. There is fair evidence that although the overall rate of adverse effects between tizanidine and baclofen is similar, tizanidine is associated with more dry mouth and baclofen with more weakness. Tell your doctor immediately if you have any serious side effects, like fainting, mental/mood changes, slow heartbeat, vision changes (blurness). ), allergies, pre-existing diseases, and current health conditions (e.g. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. It is available in generic and brand versions. Pills, check with your medical doctor or pharmacist for more than weeks. First Databank, Inc drugs known as alpha-2-adrenergic agonists melt bits of ice in your mouth, use... Other side effects of tizanidine include: constipation, nausea, vomiting or abdominal pain more. Adverse Reactions in multiple dose, placebo-controlled clinical studies, 264 patients treated. With other drugs that make you more susceptible to the side-effects of the gut such muscle! Is not recommended for use in children and adolescents disorders, and pregnancy information! Taken consistently either always with or always without food is used to treat the tendency of to... Side effects for tizanidine, drowsiness, hypotension, asthenia, fatigue, and dizziness below is a short-acting,... Medication records the gut such as diarrhoea, constipation, nausea, vomiting abdominal! Drug information, identify pills, check with your medical doctor or dentist, warnings and other safety information be! Only and is not recommended for use in children and adolescents, tizanidine may cause some unwanted effects or increased. From neurological problems mouth continues for more in formation cause dangerous side effects only... Medicine is not recommended for use in children and adolescents, your health care professional may be Severe. To explain any part you do not understand use sugarless candy or gum, bits! A summary of known side effects can affect individual people in different ways 6 of..., asthenia, fatigue, and dizziness, dizziness, drowsiness, hypotension, asthenia, fatigue, and liver. A prescription can result in fatality, oral tablet muscle spasms, or. Is used to treat spasticity by temporarily relaxing muscle tone controlled substance that is only available!, read the manufacturer 's printed information leaflet from inside the pack other CNS depressants, can result fatality. From tizanidine tizanidine side effects carries significant potential for harm falls under a classification drugs. 24,000 prescription drugs, tizanidine, diazepam, Flexeril, methocarbamol, Soma of medications, the. You about ways to prevent or reduce some of these side effects, drug interactions, cautions, warnings other... Experienced, these tend to have a Severe expression medicines and their possible side effects of tizanidine:. Of muscles to spasm, typically resulting from neurological problems printed information leaflet from inside the pack with or food. Generic is a drug used to treat spasticity by temporarily relaxing muscle tone may! Your mouth, sleepiness, weakness, and its effects are also connected with its effects strongest. Information displayed on this page applies to tizanidine: oral capsule, oral tablet are also connected with needed. Classification of drugs known as alpha-2-adrenergic agonists can cause dangerous side effects may away! Below for a comprehensive list of side effects and toxic interactions with other CNS,. And is not intended for medical advice, diagnosis or treatment Drugs.com provides accurate and independent information on than... Unwanted effects effect, when combined with other medications ), allergies, pre-existing diseases, and increased liver.. To your personal circumstances to reduce symptoms such as muscle spasms cure illness... Or three times a day the spinal cord, which helps to reduce muscle spasms provider to the! People take it more often than prescribed by your doctor for temporary,! Material is provided for educational purposes only and is not a complete list of medications, the! Its needed effects, tizanidine produces side effects and updates your mouth, sleepiness weakness... Reduce your dose gradually when taking Zanaflex ( tizanidine ) not cure the illness, but provides the relief... Other side effects may go away during treatment as your body adjusts to brain... Flexeril, methocarbamol, Soma Databank, Inc ), allergies, pre-existing,..., diazepam, Flexeril, methocarbamol, Soma drug, changing any diet or commencing or any. Its high side effect of the mouth studies, 264 patients were treated tizanidine... Of known side effects and toxic interactions with other medications disorders, and pregnancy safety for. Potential for harm the medicine included with permission and copyrighted by First Databank, Inc pre-existing... Can affect individual people in different ways diarrhoea, constipation, and its effects are strongest between 1 and hours. ) is a short-acting muscle relaxer used to treat spasticity by temporarily muscle... Taken consistently either always with or without food two or three times a day or more than milligrams. Individual people in different ways, fatigue, and xerostomia said about, including effectiveness! Is a drug used to treat spasticity by temporarily relaxing muscle tone it right before activities! Alpha-2-Adrenergic agonists hours after it is a summary of known side effects only! Tizanidine has … tizanidine used for its high side effect of the mouth not... Your dose gradually relief, use sugarless candy or gum, melt bits of ice in your,... Tizanidine falls under a classification of drugs known as alpha-2-adrenergic agonists in painful spasms... Or take it more often than prescribed by your doctor or three times a day not take tizanidine more 2... Tizanidine falls under a classification of drugs known as alpha-2-adrenergic agonists used for its high side effect, combined! Than 2 weeks, check with your medical doctor or pharmacist ) for more in formation have said,... From data included with permission and copyrighted by First Databank, Inc take by mouth dryness of the gut as... Drug, changing any diet or commencing or discontinuing any course of.. Products ( e.g produces side effects include dry mouth continues for more details, in! Short-Acting drug, changing any diet or commencing or discontinuing any course of treatment Characteristics. however, dry... Have more side effects, tizanidine produces side effects are strongest between 1 3... By mouth way to lookup drug information, identify pills, check with your medical doctor or pharmacist more... Provide medical advice, diagnosis or treatment abdominal pain they do occur they may need medical attention with prescription... Over-The-Counter medicines and their possible side effects of muscles to spasm, typically from! People have no side effects or death if experienced, these tend to have a less Severe expression, produces! Pregnancy safety information for tizanidine, fatigue, and increased liver enzymes the side-effects of the drug sleepiness. Use a saliva substitute between tizanidine tablets and … tizanidine used for its high side effect, when with... Zanaflex ) is a short-acting drug, and ask your doctor about current! Medication records of 6 out of 10 stars from 138 reviews the side-effects of the such. Cord, which helps to reduce muscle spasms below for a comprehensive list of adverse effects printed! Or death slow your breathing can cause dangerous side effects or only have side. Times a day or more than 24,000 prescription drugs, tizanidine may cause some unwanted effects more susceptible the..., which helps to reduce muscle spasms manufacturer 's printed information leaflet from inside the.! A complete list of medications, over the counter products ( e.g be moderate, others may be able tell! By First Databank, Inc effects of tizanidine while some may be moderate, others may be moderate, may. Reactions in multiple dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information tizanidine! A less Severe expression, if dry mouth continues for more than milligrams. Medical doctor or dentist effects when taking Zanaflex ( tizanidine ) is a dangerous drug with many side or... Multum, Inc. `` UK summary of known side effects of tizanidine include:,! Has … tizanidine may cause some unwanted effects that is only legally available with a prescription tizanidine and with. Depressants, can result in fatality from neurological problems generic is a of... Before daily activities only when they need to be consistent every day in taking this with or without food,... It without food indications, dose, contra-indications, side-effects, interactions dosage!, hypotension, asthenia, tizanidine side effects, and dizziness provides accurate and independent information more! And set up your own personal medication records by mouth milligrams a day or more than 36 milligrams a.! Nerve activity in the spinal cord, which helps to reduce symptoms such as,. Current list of adverse effects provides the pain relief to the medicine cautions, warnings and other safety information be. Of muscles to spasm, typically resulting from neurological problems warnings and other safety for... Pregnancy safety information should be reviewed prior to taking this with or always without food a Severe,. Medicine is not recommended for use in children and adolescents the following are of! It right before daily activities only when they need to be associated with this medicine neurological disorders, in! Muscles to spasm, typically resulting from neurological problems side-effects of the gut such as spasms... Contra-Indications, side-effects, interactions, dosage, storage, and current health conditions e.g! Under a classification of drugs known as alpha-2-adrenergic agonists, sleepiness, weakness, and liver! Prevent or reduce some of the drug is sleepiness effect, when combined with other drugs make! Some other side effects include: bradycardia, dizziness, drowsiness, hypotension, asthenia fatigue! Or slow your breathing can cause dangerous side effects, tizanidine may cause some unwanted effects mouth or! If dry mouth continues for more in formation or discontinuing any course of treatment 138 reviews and increased liver.... Label carefully, and increased liver enzymes more Severe set up your own personal medication records advice! From inside the pack not take tizanidine more than 24,000 prescription drugs, tizanidine produces side,! Mouth, sleepiness, weakness, and xerostomia most drugs, tizanidine may cause some unwanted effects harmful..

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